• Users Online: 162
  • Print this page
  • Email this page
Year : 2022  |  Volume : 7  |  Issue : 2  |  Page : 91-96

Seropositivity of COVID-19 asymptomatic nurses using Anti-SARS-CoV-2 nucleocapsid antibodies

1 Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, Najran, Saudi Arabia
2 Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia

Correspondence Address:
Dr. Ahmad A Alshehri
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, Najran 1988
Saudi Arabia
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/KKUJHS.KKUJHS_28_22

Rights and Permissions

Background: Anti-SARS-CoV-2 antibodies in symptomatic and asymptomatic cases provides helpful insight about its clinical implications. Aims and Objectives: The aim of this study is to determine anti-nucleocapsid IgG antibodies in nurses, qualitatively, both in asymptomatic and symptomatic nurses, and to determine the rate of asymptomatic cases. Second, to compare antibody reactivity from asymptomatic and symptomatic subjects. Materials and Methods: Samples were collected from four hospitals in the Southern Region, Najran, Kingdom of Saudi Arabia (KSA). Quantitative enzyme-linked immunosorbent assay from Epitope Diagnostic, Inc were used to measure the level of anti-nucleocapsid (anti-NC) antibodies in nurses. Results: One hundred twelve samples tested positive for antibodies (70%). Other variables were assessed, including age, gender, ABO blood group, and nationality. A significant difference was found between asymptomatic nurses vs. those with negative antibodies (*P = 0.0147), suggesting they could have transmitted SARS-CoV-2 unknowingly. Forty-one nurses (25.6%) were symptomatic, while 99 nurses were asymptomatic (61.8%). Conclusion: In this study, 112 nurses (70%) tested positive for the anti-NC antibodies, 41 (25.6%) were symptomatic, 99 (61.8%) were asymptomatic, and 48 (30%) were anti-NC antibody negative. Future work should focus on the association of respiratory disease with the concentration of antibodies, and if antibodies wane rapidly after COVID-19 infection.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded43    
    Comments [Add]    

Recommend this journal